Noxious input to the spinal cord is known to produce central sensitization, which consists of allodynia , exaggeration of pain, and punctuate hyperalgesia , extreme sensitivity to pain. Two types of mechanical hyperalgesia can occur: 1) touch that is normally painless in the uninjured surroundings of a cut or tear can trigger painful sensations (touch-evoked hyperalgesia), and 2) a slightly painful pin prick stimulation is perceived as more painful around a focused area of inflammation (punctuate hyperalgesia). Touch-evoked hyperalgesia requires continuous firing of primary afferent nociceptors, and punctuate hyperalgesia does not require continuous firing which means it can persist for hours after a trauma and can be stronger than normally experienced. In addition, it was found that patients with neuropathic pain, histamine ionophoresis resulted in a sensation of burning pain rather than itch, which would be induced in normal healthy patients. This shows that there is spinal hypersensitivity to C-fiber input in chronic pain. 
When injected daily Winstrol Depot can become a very expensive compound. It also has the disadvantage that, because of the fre-quent injections, the already-mentioned scar tissue will develop in the gluteal region (buttocks) which leads many athletes to inject Winstrol in their shoulders, arms, legs or even calves. Although this was originally intended as an expedient, injecting Winstrol Depot into certain muscles has become increasingly popular since athletes have noticed that this leads to an accelerated growth of the affected muscle. An American pro bodybuilder who is known for his cross striated, horseshoe- shaped triceps owes this in considerable part to his regular “triceps Winstrol-Depot injections.” A confusion with the also often used Esiclene is excluded. Athletes who want to avoid daily injections usually take 2-3ml Winstrol Depot twice a week. in the . injectable stanozolol is manufactured only for veterinary medicine. It is distributed under the name Winstrol V .