Androgens stimulate protein synthesis in muscle, and they usually do not affect the overall synthesis in the organism. Androgens stimulate the production of red blood cells by synthesis and secretion stimulation of erythropoietin, direct stimulation of hematopoiesis in bone, marrow stimulation and inclusion of iron ions in the red blood cells. Although the use of androgens causes a significant increase in hematocrit and hemoglobin levels. At the same time in healthy men, when testosterone enanthate is applied in amounts of 200 mg per week, during 16 weeks cycle, the significant increase in the number of red blood cells and the increase in the hematocrit and hemoglobin were observed.
Males with Delayed Puberty: Various dosage regimens have been used; some call for lower dosages initially with gradual increases as puberty progresses, with or without a change in maintenance levels. Other regimens call for higher dosages to induce pubertal changes and lower dosages for maintenance after puberty. The chronological and skeletal ages must be taken into consideration, both in determining the initial dose and in adjusting the dose. Dosage is generally within the lower ranges and only for a limited duration, for example, 4 to 6 months. X-rays should be taken at appropriate intervals to determine the amount of bone maturation and skeletal development (see INDICATIONS and WARNINGS).